http://www.researchcareer.com.au/
A PhD scholarship is offered, for a student to work on the project: Development, optimisation and manufacturing of novel bespoke technologies for AAV-based gene therapies for neurological disorders.
This PhD project aims to develop safe, practical, and affordable gene therapy treatment options focused on patients suffering from debilitating neurological conditions, such as motor neuron disease. Furthermore, this project seeks to improve the manufacturing process of the bioengineered vehicles of gene therapy (termed 'vectors') through the development of novel bespoke manufacturing technologies. The vectors used in this project will be recombinant adeno-associated virus (rAAV), the current vector of choice for gene delivery. The goal of this project is to improve personalised gene therapy treatments to result in readily accessible, affordable, and ready for use in clinical practice. As this project will be primarily based at the Westmead Precinct, the PhD candidate will have access to the cutting-edge technology and expertise present at this world-class facility. Throughout this project, they will be able to master a range of sought-after skills in viral vector design, manipulation of the AAV genome, vector manufacturing, and bioinformatic analysis, providing them with highly sought-after specialised skills.
Children’s Medical Research Institute (CMRI) is an award-winning state-of-the-art medical research facility, with over 100 full-time scientists dedicated to researching the genes and proteins important for health and human development. CMRI is located at Westmead, a major hub for research and medicine in NSW, and is affiliated with the University of Sydney. We are easy to access by public transport.
Benefits
This scholarship is valued at $40,000 per annum and is tenable for up to 3.5 years.
Who's eligible
You must:
Preference will be given to applicants who can demonstrate they have experience in one or more of the following:
Background
This scholarship is funded by New South Wales (NSW) Health and the University of Sydney as part of the NSW Health Gene and Cell Therapy PhD Program.
Applications
Applications MUST be submitted here: https://www.sydney.edu.au/scholarships/c/scholarship-in-aav-based-gene-therapies-for-neurological-disorde.html
Closing date: 11 February 2022 at 11.59 pm
Contact Prof Leszek Lisowski for more information: llisowski@cmri.org.au